Gene ATLAS is a large database of associations between hundreds of traits and millions of variants using the UK Biobank cohort.

The associations have been computed using 452,264 UK Biobank White British individuals. To avoid having to remove the large amount of related individuals present on the study, the associations have been computed using Mixed Linear Models in a large supercomputer using DISSECT. The objective of the current database is to benefit the research community by making a searchable atlas of genetic associations that help researchers to query associations results in an easy way, without the need to incur in the high computational costs required to analyze the UK Biobank large cohort.



Million Variants

This work has been done at the Roslin Institute and MRC-HGU within the Albert Tenesa’s group with the contributions of Oriol Canela-Xandri and Konrad Rawlik.